|
KMID : 0931320190190040236
|
|
대한상부위장관.헬리코박터학회지
2019 Volume.19 No. 4 p.236 ~ p.244
|
|
|
Change in Size of Gastric Hyperplastic Polyps after Helicobacter pylori Eradication: A Prospective Study
|
|
Yoo Ah-Young
Park Jong-Jae
Joo Moon-Kyung
Lee Beom-Jae
Chun Hoon-Jai
Lee Sang-Woo
|
|
|
Abstract
|
|
|
Background/Aims: Helicobacter pylori (H. pylori) eradication is known to be effective for reducing the size of gastric hyperplastic polyps (HPPs). This study investigated the change in size of gastric HPPs after H. pylori eradication.Materials and
Methods: This was a prospective study that enrolled 25 H. pylori-positive patients diagnosed as having HPPs at Korea University Guro Hospital between July 2015 and July 2016. If the patient wanted to receive eradication therapy, medication was given. If the patients refused eradication, only clinical follow-up was performed. All patients were subsequently followed up with endoscopic examination to determine any change in polyp size.
Results: Eighteen of the 25 H. pylori-positive patients diagnosed as having HPPs were given an eradication regimen, and 17 were confirmed to have achieved successful eradication. Twelve (70.8%) of the 17 patients in the eradication group showed ≥50% reduction in size, while two (25.0%) of the eight patients in the non-eradication group showed 50% reduction. The polyp regression rate was significantly higher in the eradication group (P=0.03). A multivariate analysis revealed that H. pylori eradication (OR, 40.047; 95% CI, 1.112~1442.767; P=0.044) and female sex (OR, 12.947; 95% CI, 1.038~161.503; P=0.047) were significant predictive factors of HPP regression.
Conclusions: H. pylori eradication is an effective therapeutic modality for gastric HPP regression.
|
|
|
KEYWORD
|
|
|
Helicobacter pylori, Polyps, Stomach neoplasms
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|